患者男性,28岁,78kg,因“淋病”来诊。给予盐酸四环素治疗,已知该药的口服吸率收

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问题:

患者男性,28岁,78kg,因“淋病”来诊。给予盐酸四环素治疗,已知该药的口服吸率收为77%,血浆蛋白结合率为65%,表观分布容积为0.5L/kg,消除半衰期为10.6小时,58%从尿中以原形排出,对淋病的最小抑菌浓度(MIC)为25~30mg/L。

每6小时给药一次,维持剂量应为()

A.345.6mg

B.388.2mg

C.425.6mg

D.480.5mg

E.546.6mg

F.632.8mg

考点:临床药学(医学高级)药动学与生物利用度研究药动学与生物利用度研究题库
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完形填空。
     In 1989 an 8.2 earthquake almost flattened Los Angeles, killing over 30,000 people in less than four minutes.
A father rushed to where his son was   1   to be, only to discover that the building was flattened.
     But he remembered the   2   he had made his son: "I'll always be there for you!" Tears began to fill his eyes.
Although it looked   3  , he remembered his words. 
       4   his son's classroom would be in the back right corner of the building, he rushed there and started   5  .
     Other parents tried to pull him off what was left of the school, saying " It's too late! They're all dead! You
can't   6   !"
     To each he   7   : "Are you going to help me?" And then he went back to his digging. The fire fighter   8   and
tried to pull him away: "Fires are breaking out, explosions are happening everywhere. You're   9  ."To which this
loving,   10   father asked:"Are you going to help me?"
     He went on  11  he needed to know,"Is my boy alive or is he dead?" He dug for eight hours…l2 hours…36
hours…then, in the 38th hours, he pulled back a large stone and  12   his son. He  13  : "ARMAND!"He heard
back:" Dad?It's me, Dad! I told the other kids not to  14 . I told them that if you were  15 , you'd save me and
when you saved me, they'd be saved. You  16 , no matter what happens, I'll always be there for you!" "What's
going on in there?" the father asked.
      "There are l4 of us  17  out of 33, Dad. We're scared but  18   you're here. When the building collapsed, it
  19  a triang1e (三角形), and it saved us."
      "  20 , boy!"
     "Let the other kids out first, because I know you'll get me! I know you'll always be there for me!"
( )1. A. reported   
( )2. A. decision   
( )3. A. annoying   
( )4. A. Recalling  
( )5. A. wandering  
( )6. A. help       
( )7. A. whispered  
( )8. A. looked up  
( )9. A. in place   
( )10. A. caring    
( )11. A. when      
( )12. A. saw       
( )13. A. screamed  
( )14. A. relax     
( )15. A. brave     
( )16. A. complained
( )17. A. lying     
( )18. A. thankful  
( )19. A. built     
( )20. A. Stand out 
B. supposed          
B. mistake           
B. satisfactory      
B. Seeing            
B. digging           
B. wait              
B. murmured        
B. stood up          
B. in danger         
B. smiling           
B. after             
B. met               
B. waved             
B. worry             
B. active            
B. promised          
B. sleeping          
B. hopeful           
B. designed          
B. Keep up         
C. announced          
C. promise            
C. embarrassing       
C. Hearing            
C. crying             
C. suffer             
C. responded          
C. climbed up         
C. in charge        
C. leading           
C. if                
C. heard             
C. nodded            
C. hurry             
C. alive             
C. remarked          
C. discouraged       
C. careful           
C. made              
C. Take it easy      
D. said               
D. suggestion         
D. hopeless           
D. Predicting         
D. filling            
D. fail               
D. explained          
D. showed up          
D. in relief          
D. promising          
D. because            
D. felt               
D. argued             
D. flee               
D. strong             
D. stated             
D. left               
D. useful             
D. circled            
D. Come out         
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患者,男,54岁,1年前日常活动后出现胸骨后疼痛,海日2~3次,近2个月发作次数增多,每日5~6次,轻微活动也能诱发,发作时心电图ST段呈一过性压低。

药物治疗可选用

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B.氯吡格雷口服

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临时用电的检查内容包括( )。

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